A nanopore is a pore or channel structure having a size ranging between 1 to 100 nm. Because of the similar size, the strong interactions between the transporting ions/molecules and nanopores will affect the ionic transfer. This leads the system to generate new signals that are different from the macroscopic system. Based on these properties, nanopores are extensively been used in the applications of single molecule detection, DNA sequencing, bionic sensor, enzymatic reaction kinetics, drug delivery, and many more. The traditional nanopore is mainly dependent on the biological protein channel, but their limited tunability and poor stability make them difficult for practical applications. Therefore, solid-state nanopore is a new direction of analytical chemistry and since 1990 it has developed rapidly. A large number of materials and methods have been used to fabricate the solid-state nanopores. Among those solid-state nanopores, conical nanopores based on glass nanopipette have a superior advantage. They possess asymmetrical geometry and a distinct surface charge distribution. However, pulling glass nanopipettes with the aperture less than 10 nm becomes challenging. Here, we solved this problem by fabricating a porous material (COF) at the tip of the glass nanopipette with a single pore of 150 nm. This design decreases the aperture size of the tip to a few nanometers, which makes it perfect to study the ion mass transfer in a confined space. Moreover, they have high stability, controllable diameter, adjustable channel length, and surface properties make them suitable for integration into devices.
Keywords:
Imine COF, Turbostratic Effect, Slipping Layers, Exfoliation, Covalent Organic Frameworks, Theta Micropipette, Mass Transfer, Gas Mapping, SECM, Humidity Imaging Probe

My name is Saud Asif Ahmed and I obtained my Ph.D. in Chemistry from Nanjing University, China on the research topic “Nanochannels of Covalent Organic Frameworks: A Study on Fabrication and Ionic Transfer”, in June 2020. Among my Ph.D. advisors was Prof. Xing-Hua Xia, a nationally renowned and top-ranked professor in electrochemistry in China. 
I was awarded a fully-funded scholarship for 5 years (2015-2020), from the Chinese Scholarship Council, China, for my Ph.D. degree. During my Ph.D., I was selected in the top 3 for the “Best International Student of the year in Nanjing University (2018) and also the "Chemistry Star" award of Department of Chemistry and Chemical Engineering, Nanjing University in 2019. 
Currently, I am working as a joint post-doctoral researcher in Shenzhen Research Institute of Guangdong Ocean University, Shenzhen, and Nanjing University, Nanjing China. Nanjing University is considered among the top universities in the world (QS Ranking: 131) and the department of chemistry and chemical engineering of Nanjing university ranks among the top 50 in the world.
My research work is mainly focused on electroanalytical chemistry, electrochemical sensing, mass transport of ions through porous materials using single and double barrel nanopipettes. I have more than 14 publications, in journals like Angewandte Chemie, Nano Letters, Analytical Chemistry, Chemical Communications, and Chemistry, A European Journal. Furthermore, several of my articles are in the process of publishing.