| Biography | |
|---|---|
 Dr. Lalit M. Pandey Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India |
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| Title: Antibacterial nanocomposite scaffolds of Chitosan, Carboxymethyl Cellulose and Zn & Fe integrated Hydroxyapatite (Chitosan-CMC-FZO@HAp) for biomedical applications | |
| Abstract:
The nanocomposite scaffolds are being explored for different biomedical applications including bone tissue engineering. However, the desired degradation and non-antibacterial behaviour are the major challenges for the researchers. In this regard, nanocomposites offer the flexibility to develop multifunctional biomaterials. In the present study, we first designed Fe(III) doped ZnO integrated hydroxyapatite ZFHAp nanoparticles followed by preparation of the natural biopolymer-based chitosan- carboxymethyl cellulose-ZFHAp scaffolds. The physical and chemical properties of the prepared nanocomposite were characterized. The swelling and degradation of the prepared scaffolds were linearly related. The presence of ZFHAp in the scaffolds enabled tuning of the pore size and degradation behaviour. The scaffolds with 5 % ZFHAp (SCA-5) exhibited self-antibacterial activities along with excellent cell proliferation ability. The present study designates the SCA-5 nanocomposites as plausible scaffolds for bone tissue engineering. Keywords: Chitosan; Carboxymethyl cellulose; Nano-hydroxyapatite; Nano-biocomposite scaffold; Degradation; Porosity; Cell proliferation; Self-antibacterial activity | |
| Biography: Dr. Lalit Pandey, currently an Associate Professor in the Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, obtained Ph.D. in Chemical Engineering from the Indian Institute of Technology, Delhi. He was awarded Erasmus Mundus India4EU Fellowship to pursue his research at Laboratoire des Matériaux et du Génie Physique (LMGP), Grenoble-INP, France, for 18 months during 2010 to 2012. Before joining the IIT Guwahati, he worked as a Scientist with the Central Pollution Control Board, Ministry of Environment & Forests, Government of India, from 2009 to 2014 and researched on water and air pollution in agro-based industries. He has received several awards, including the BRSI Malaviya Memorial Award (Young Faculty) 2020, the Shastri Covid-19 Pandemic Response Grant (SCPRG) 2020, the DSTUKIERI Award 2018, the IEI (The Institution of Engineers [India]) Young Engineers Award 2017, Innovation in Science Pursuit for Inspired Research (INSPIRE) Faculty Award 2014, and Early Career Research Award from Science and Engineering Research Board (SERB) by Department of Science & Technology, Government of India. Dr. Pandey’s research focuses on: biointerfaces and biomaterials, biochemical engineering and environmental biotechnology. He has published over eighty five scientific articles in international journals, over twenty nine book chapters and is Associate Editor of two international journals: “Frontiers in Bioengineering and Biotechnology”, and “Frontiers in Materials”. In addition, he serves as a reviewer for several peer-reviewed journals. Dr. Pandey has co-edited three books, titled “Biointerface Engineering: Prospects in Medical Diagnostics and Drug Delivery”, “Microbial Enhanced Oil Recovery: Principles and Potential” and “Nanoscale Engineering of Biomaterials: Properties and Applications”, published by Springer Nature. He is a life member of the International Association of Engineers (IAENG), the Indian Institute of Chemical Engineers (IIChE), the Biotech Research Society, India (BRSI), and Nano and Molecular Society (India). | |
